Our best bet for the Big 12’s Week 2 card, in terms of point spreads, is Houston (+29.5) vs. Oklahoma; see below for more advice (including parlay odds) for both spreads and over/unders.

With Week 2 of college football about to begin, stay on top of the latest betting trends with our preview below.

Best Big 12 spread bets for Week 2

College football odds courtesy of BetMGM SportsbookOdds updated Wednesday at 11:36 p.m. ET. For a complete list of sports betting odds, visit the USA TODAY Sports Betting Odds Center.

Prediction: Houston +29.5 vs. Oklahoma

  • Game information: Houston Cougars vs. Oklahoma Sooners
  • Projected Winner: Oklahoma by 20.4 points
  • Game time: 19:45 ET
  • Date of the game: September 7th
  • TV Channel: SEC Network
  • Live broadcast: Fubo

Prediction: Oklahoma State -7.5 vs. Arkansas

  • Game information: Arkansas Razorbacks vs. Oklahoma State Cowboys
  • Projected Winner: Oklahoma State by 14.7 points
  • Game time: 12:00 pm US Eastern Time
  • Date of the game: September 7th
  • TV Channel: alphabet
  • Live broadcast: Fubo

Prediction: Kansas -5.5 vs. Illinois

  • Game information: The Kansas Jayhawks take on the Illinois Fighting Illini
  • Projected Winner: Kansas by 12.5 points
  • Game time: 7:00 pm US Eastern Time
  • Date of the game: September 7th
  • TV Channel: Fox 1 Sports
  • Live broadcast: Fubo

Prediction: Kansas State -9.5 vs. Tulane

  • Game information: Kansas State Wildcats at Tulane Green Wave game
  • Projected Winner: Kansas State by 16.5 points
  • Game time: 12:00 pm US Eastern Time
  • Date of the game: September 7th
  • TV Channel: ESPN
  • Live broadcast: Fubo

Prediction: Mississippi State +6.5 vs. Arizona State

  • Game information: Mississippi State Bulldogs vs. Arizona State Sun Devils
  • Projected Winner: Arizona State by 0.6 points
  • Game time: 22:30 ET
  • Date of the game: September 7th
  • TV Channel: ESPN
  • Live broadcast: Fubo

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